Ioannis Ragoussis

Dr. Ragoussis is the scientific lead of the Genomic Platforms of the McGill University Genome Center, and member of McGill’s Integrative And Quantitative Biology Initiative. With funds from CFI, he has established an Advanced Genomics and Single Cell Genomics Laboratory, accelerating research in cancer and other diseases. Current main projects include the Genome Canada GAPP “Detecting Ovarian Cancer Early” where the lab is developing high throughput, ultra-high sensitivity somatic mutation detection methodologies for gynecological cancer screening, the CRUK Grant Challenge Program “STORMing Cancer” applying single cell genomic methodologies in gastric, lung and colon cancer analysis, development of spatial transcriptomics and nuclei based genomics to analyze CNS funded by Eli Lilly, the Genome Canada LSARP “Tackling Childhood Brain Cancer at the root to improve survival and quality of life” where linked read and long read technologies are being developed to identify structural rearrangements in pediatric tumors, the Genome Canada LSARP “Applying Precision Medicine Technologies in Canada to Prevent Antibody Mediated Rejection and Premature Kidney Transplant Loss” where technologies for sequencing the highly complex human MHC are being developed, with further work involving  Ovarian and Breast Cancer Genetics funded by CIHR, the development of new genomic approaches in Sterile Insect Technique applications funded by the International Atomic Energy Authority  in form of a Coordinated Research Program and deer dick population genomics in Lyme Disease funded by MI4. Further technological developments in NGS are planned as part of a program with the NRC laboratory in 2021 and as part of the CIHR VOC Network. The lab takes part in laboratory-based post graduate courses in Genomics at McGill and in Transcriptomics at the Sanger Institute (UK).